First textbook in geriatrics, pioneering medical care for the elderly.

First textbook in America on thoracic surgery.

First Department of Geriatrics and Adult Development in a medical school in the United States.

First extensive, mandatory rotation for medical students in a nursing home.

First center in New York to use state-of-the-art audiovisual systems combined with specially-trained actors to help students develop the communication skills essential to a successful physician-patient relationship.

First to describe numerous disorders including: Brill's Disease, Buerger's Disease, Churg-Strauss Disease, collagen disease, Crohn's Disease, eosinophilic granuloma of bone, Glomus Jugalare Tumor, Libman-Sacks Disease, Moschcowitz Disease, Tay-Sachs Disease.

Identified Koplik's Spots as a diagnostic sign of measles.

Paved the way for modern blood banks by describing the minimum amount of sodium citrate needed to keep blood from clotting.

Discovered that foreign proteins were responsible for chills after intravenous administration of fluids and blood.

Described Shwartzman Phenomenon: necrotic reaction to filtrates containing endotoxin of gram-negative bacteria (This is the concept behind how TB skin testing works.)

Developed the polyacrylamide gel electrophoresis method of separating proteins.

Developed the concept of subcellular pathology.

First to demonstrate that human cancer may depend largely upon multiple factor interactions, such as cigarettes and asbestos.

First discovery of a chemical that induces cancer cells to return to their normal patterns of development.

Isolated and cloned the complete structural gene for human tissue factor, the protein that activates blood coagulation.

Demonstrated how asbestos can cause cancerous changes in the DNA of cells.

Identified the gene for Marfan Syndrome, an often fatal connective tissue disorder.

Identified a marker that is now commonly used to determine if a women is at risk for preterm birth.

First to perform blood transfusions with routine compatibility tests and to point out that blood groups are hereditary.

Developed and first to use electrical fulguration of bladder tumors via the cystoscope.

First pulmonary lobectomy for inflammatory disease.

Developed a practical positive pressure anesthesia machine and was first to apply the method clinically.

Introduced the use of peruterine insufflation of the fallopian tubes for the diagnosis and treatment of sterility in women.

Developed the first successful cardiac stress test.

Developed the concept of the broncho-pulmonary segment, now used in surgery and medicine of the lung.

Developed intensive short-term medical treatment of syphilis with arsenicals.

Pioneered the use of stapes mobilization operation for alleviation of particular kinds of deafness.

Developed first practical bipolar coagulator, a standard apparatus for neurosurgical operations.

First use of a sequential combination regimen of chemotherapy for adjuvant treatment of ovarian and breast cancer.

Created the first genetically engineered vaccine—an influenza vaccine.

Established the Mesothelioma Therapy Research Program in the Environmental Science Laboratory and the Department of Neoplastic Diseases, the first organized effort to control and cure an environmental cancer.

First use of platinum in the United States for the treatment of ovarian cancer.

Developed an in vitro fertilization technique for helping sperm cells to penetrate egg cells.

First blood transfusion into the tiny vein of an unborn fetus.

First in New York State to do a liver transplant.