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Introduction to Clinical Trials
Introduction to Clinical Trials
Review frequently asked questions and introductory information about clinical trials.
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List of Clinical Trials
Open Clinical Trial
Endothelial Function in Fibromuscular Dysplasia.
The purpose of this study is to evaluate blood vessel function in subjects with fibromuscular dysplasia and to determine whether there are any changes in vascular function as compared to healthy age, gender, and ethnic origin matched control subjects.
An ultrasound, a non-invasive test, will be performed on the brachial artery (blood vessel in the upper arm), and carotid arteries (blood vessels in the neck). In addition, blood pressure will be performed on the ankles and arms. The non-invasive ultrasound tests will be performed in the morning and each subject must fast for 12 hours prior to the study. If you qualify and complete the study you will be compensated for your participation.
Compensation
Y
Inclusion
You may qualify for participation in this study because you have fibromuscular dysplasia or you are an age, gender, and ethnic origin matched healthy contol subject. All subjects must be 18 years of age or older.
Exclusion
1) Current smoking.
2) History of alcohol abuse.
3) Recreational drug use.
4) Subjects taking vasoactive hypertensive medications including phosphodiesterase type 5 (PDE-5) inhibitors such as sildenafil citrate (Viagra, Revatio), tadalafil (Cialis), and vardenafil (Levitra); endothelin receptor antagonists such as bosentan (Tracleer); and prostacyclin derivatives such as epoprostanol (Flolan) and trepostinil (Remodulin).
Research Study Site
Mount Sinai Medical Center
Department Name
MSSM Cardiovascular Institute
Contact Information
Nicole Wake [Coordinator]
Vascular Coordinator
nicole.wake@mssm.edu
212.241.9454
GCO Number
09-0021
IRB Start/End Date
April 6, 2009 to March 16, 2010
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