Intrathecal Dexmedetomidine Vs Epinephrine

ID#: NCT06418308

Age: 18 - 55 years

Gender: Female

Healthy Subjects: No

Study Phase: Phase 4

Recruitment Status: Recruiting

Start Date: September 17, 2024

End Date: May 01, 2025

Contact Information:
Talia Scott, MD
720-212-7448
Summary: Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.
Eligibility:

Inclusion Criteria:

- Pregnant patients

- aged 18-55 years

- presenting for scheduled primary or secondary cesarean section

- candidates for single shot spinal anesthesia singleton pregnancy

Exclusion Criteria:

- patient refusal of spinal anesthetic

- if patient is not a candidate for spinal anesthesia due to history of coagulopathy, elevated intracranial pressure, infection at site of injection, etc.

- emergency cesarean section

- preexisting motor or sensory deficit

- suspected pre-eclampsia

- patient receiving combined spinal-epidural as anesthetic technique

- BMI > 40
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