We've found 874 total result s
Randomized, Double-blind [study drug at 25mg, 15 mg or a placebo] Duration: 7 months Study visits: 9 study visits (7 Onsite and 2 telephone visits) Study activities: Blood, Urine and Stool sample collection Complete surveys/questionnaires Eye Exam, ECG Compen...
Age: 18 years - 66+
Gender: N/A
The Sweat Sensor Study at Mount Sinai aims to measure and monitor markers of inflammation and the immune system, such as C-reactive protein and calprotectin, continuously in the sweat using a wearable sweat sensing device. Our hope is that this wearable device will even...
Age: 18 years - 66+
Gender: All
Seizure emergencies involving prolonged seizures are unlikely to stop without treatment, may become more difficult to control with time, and may lead to significant morbidity and mortality. This confirmatory study (EP0162) will investigate the efficacy and safety of a s...
What is the purpose of the study? Many patients with Crohn’s disease or ulcerative colitis are women who are diagnosed with the disease during peak childbearing years. Both patients and providers frequently ask whether IBD, IBD surgery, or IBD medications affect a...
The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency intervention, Resilient Together for Dementia (RT-D), aimed at preventing chronic emotional distress and preserving quality of life among dyads a...
Age: 65 years - 66+
Gender: All
The APEX study is a multicenter, observational study designed to capture longitudinal follow-up of plasma biomarkers and cognitive and functional assessments on individuals who screen failed in the AHEAD study over approximately 4 years. Approximately 1000 parti...
Age: 55 - 80 years
Gender: All
The overall goal of this study is to facilitate care improvements for bladder cancer patients with locally advanced or metastatic disease by designing and evaluating a patient need assessment screening tool to be used, in the future, as standard screening measure. Adult...
Age: 18 - 89 years
Gender: All
Black and Latina women experience disparities in supportive and palliative care access and outcomes. The goal of the proposed pilot study is to evaluate the feasibility and acceptability of a community navigator delivered supportive care intervention for historica...
Age: 18 years - 66+
Gender: Female
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/m^2 or higher and Atherosclero...
Age: 45 years - 66+
Gender: All
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO sys...
Age: 22 years - 66+
Gender: All
The aim of this study is to assess rates of neonatal hypoglycemia with differing intrapartum glucose protocols. Currently at this time there is no guidance from professional medical organizations about when and how frequent to assess maternal glucose levels intrapar...
Age: 18 years - 66+
Gender: Female
Keloids are common, benign cutaneous overgrowths that manifest clinically as raised, hypertrophic, often hyperpigmented lesions which are formed in response to dermal injury or idiopathic stimuli. Although keloids are a common disease, it's exact incidence and pre...
Age: 18 years - 66+
Gender: All
This is a partially blinded randomized controlled phase II pilot study comparing Poly-ICLC (Hiltonol®) treatment vs no treatment, for prostate cancer participants on active surveillance.
Age: 18 years - 66+
Gender: Male
The purpose of this research study is to evaluate the effectiveness and safety of bimekizumab in individuals with moderate-to-severe psoriasis who have failed similar therapies. Bimekizumab improves psoriasis by suppressing a type of substance found in bodies called...
Age: 18 years - 66+
Gender: All
PlAcebo versus erector spINae pLane block for mEdical ThoracoScopy Study (PAINLESS). This is a prospective triple-blind, randomized controlled trial that evaluates the efficacy of erector spinae plane block (ESPB) with Bupivacaine in reducing pain after medical th...
Age: 18 years - 66+
Gender: All
The purpose of this study is to evaluate the effectiveness and safety of BMS-986393 in participants with relapsed or refractory multiple myeloma.
Age: 18 years - 66+
Gender: All
The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart attack or stroke. The study drug will be administered subcutaneo...
Age: 18 years - 66+
Gender: All
Chronic lower back pain (CLBP) affects approximately 20% of the global population. The study objective is to determine if impulsivity, inhibitory control, drug choice, and/or cognitive distortions predict opioid misuse and disability in patients with chronic pain. This ...
Age: 18 years - 66+
Gender: All
The purpose of this study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's Disease.
Age: 50 - 80 years
Gender: All
Optimizing health related-quality of life (HRQoL) for patients with inflammatory bowel disease (IBD), who often experience a relapsing disease course, is an essential component of care. Improving IBD disease control is linked to increased health-related quality of l...
Age: 18 years - 66+
Gender: All