Herbal remedies and supplements for weight loss
Weight loss - herbal remedies and supplements; Obesity - herbal remedies; Overweight - herbal remedies
Weight-loss Product Options
There are many over-the-counter diet products, including herbal remedies. Many of these products do not work. Some can even be dangerous. Before using an over-the-counter or herbal diet remedy, talk with your health care provider.
Nearly all over-the-counter supplements with claims of weight-loss properties contain some combination of these ingredients:
- African mango (Irvingia gabonensis)
- Aloe vera
- Aspartate
- Carnitine
- Chromium
- Coenzyme Q10
- DHEA derivatives
- EPA-rich fish oil
- Green tea
- Hydroxycitrate
- L-carnitine
- Pantethine
- Pyruvate
- Sesamin
- White kidney bean (Phaseolus vulgaris)
There is no evidence, or only very weak evidence, that these ingredients help with weight loss.
In addition, some products contain ingredients that are found in prescription drugs, such as blood pressure medicines, anti-seizure medicines, antidepressants, and diuretics (water pills).
Safety of Over-the-Counter Products
Some ingredients in over-the-counter diet products may not be safe. The Food and Drug Administration (FDA) warns people not to use some of them. Do not use products that contain these ingredients:
- Ephedrine is the main active ingredient of herbal ephedra, also known as ma huang. The FDA does not allow the sale of medicines that contain ephedrine or ephedra. Ephedra can cause serious side effects, including strokes and heart attacks.
- BMPEA is a stimulant related to amphetamines. This chemical can lead to health problems such as dangerous high blood pressure, heart rhythm problems, memory loss, and mood problems. Supplements with the herb Acacia rigidula labeled on the packaging may contain BMPEA, even though this chemical has never been found in that herb.
- DMBA and DMMA are stimulants that are chemically very similar to one another. They have been found in fat-burning and workout supplements. DMBA is also known as AMP citrate. Both chemicals can cause nervous system and heart problems.
- Brazilian diet pills are also known as Emagrece Sim and Herbathin dietary supplements. The FDA has warned consumers not to buy these products. They contain stimulant drugs and drugs used to treat depression. These can cause severe mood swings.
- Tiratricol is also known as triiodothyroacetic acid or TRIAC. These products contain a thyroid hormone, and they may increase the risk for thyroid disorders, heart attacks, and strokes.
- Fiber supplements that contain guar gum have caused blockages in the intestines and esophagus, the tube that carries food from your mouth to your stomach and intestines.
- Chitosan is a dietary fiber from shellfish. Some products that contain chitosan are Natrol and Chroma Slim. People who are allergic to shellfish should not take these supplements.
References
Hafida S, Apovian CM. Obesity and neuroendocrine control of energy stores. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, Kopp PA, eds. Williams Textbook of Endocrinology. 15th ed. Philadelphia, PA: Elsevier; 2025:chap 40.
Jensen MD, Bessesen DH. Obesity. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 201.
Keating MK, Woodruff RK, Saner EM. Management of obesity: office-based strategies. Am Fam Physician. 2024;110(2):145-156. PMID: 39172672
Lewis JH. Liver disease caused by anesthetics, chemicals, toxins, and herbal and dietary supplements. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 89.
National Institutes of Health Office of Dietary Supplements website. Dietary supplements for weight loss: fact sheet for health professionals.
Rivas García F, García Sierra JA, Valverde-Merino MI, Zarzuelo Romero MJ. Dietary supplements for weight loss and drug interactions. Pharmaceuticals (Basel). 2024;17(12):1658. PMID: 39770500
Version Info
Last reviewed on: 7/3/2025
Reviewed by: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
