Influenza (flu) vaccine (Inactivated or Recombinant): What you need to know
All content below is taken in its entirety from the CDC Inactivated Influenza Vaccine Information Statement (VIS)
Influenza vaccines are developed each year to protect people from the strains expected to be most prevalent. Viruses in the vaccine are inactivated or attenuated, so it is not possible to get the flu from the vaccine.
Vaccines are used to boost your immune system and prevent many diseases, some of which are serious or life-threatening. Vaccines “teach“ your body how to defend itself when germs, such as viruses or bacteria, invade it. After exposure to the vaccine, your immune system learns to recognize and attack the viruses or bacteria if you are exposed to them later in life. As a result, you will not become ill. Or, if you do get the illness, you will likely have a milder infection. Vaccines are very safe and very effective at protecting against certain serious diseases.
Information
Why get vaccinated?
Influenza vaccine can prevent influenza (flu).
Flu is a contagious disease that spreads around the United States every year, usually between October and May. Anyone can get the flu, but it is more dangerous for some people. Infants and young children, people 65 years and older, pregnant women, and people with certain health conditions or a weakened immune system are at greatest risk of flu complications.
Pneumonia, bronchitis, sinus infections, and ear infections are examples of flu-related complications. If you have a medical condition, such as heart disease, cancer, or diabetes, flu can make it worse.
Flu can cause fever and chills, sore throat, muscle aches, fatigue, cough, headache, and runny or stuffy nose. Some people may have vomiting and diarrhea, though this is more common in children than adults.
In an average year, thousands of people in the United States die from flu, and many more are hospitalized. Flu vaccine prevents millions of illnesses and flu-related visits to the doctor each year.
Influenza vaccines
CDC recommends everyone 6 months and older get vaccinated every flu season. Children 6 months through 8 years of age may need 2 doses during a single flu season. Everyone else needs only 1 dose each flu season.
It takes about 2 weeks for protection to develop after vaccination.
There are many flu viruses, and they are always changing. Each year a new flu vaccine is made to protect against the influenza viruses believed to be likely to cause disease in the upcoming flu season. Even when the vaccine doesn't exactly match these viruses, it may still provide some protection.
Influenza vaccine does not cause flu.
Influenza vaccine may be given at the same time as other vaccines.
Talk with your health care provider
Tell your vaccination provider if the person getting the vaccine:
- Has had an allergic reaction after a previous dose of influenza vaccine,or has any severe, life-threatening allergies.
- Has ever had Guillain-Barré Syndrome (also called "GBS").
In some cases, your health care provider may decide to postpone influenza vaccination until a future visit.
Influenza vaccine can be administered at any time during pregnancy. Women who are or will be pregnant during influenza season should receive inactivated influenza vaccine.
People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting influenza vaccine.
Your health care provider can give you more information.
Risks of a vaccine reaction.
- Soreness, redness, and swelling where the shot is given, fever, muscle aches, and headache can happen after influenza vaccination.
- There may be a very small increased risk of Guillain-Barré Syndrome (GBS) after inactivated influenza vaccine (the flu shot).
Young children who get the flu shot along with pneumococcal conjugate vaccine (PCV13) and/or DTaP vaccine at the same time might be slightly more likely to have a seizure caused by fever. Tell your health care provider if a child who is getting flu vaccine has ever had a seizure.
People sometimes faint after medical procedures, including vaccination. Tell your provider if you feel dizzy or have vision changes or ringing in the ears.
As with any medicine, there is a very remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death.
What if there is a serious problem?
An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital.
For other signs that concern you, call your health care provider.
Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Visit the VAERS website at
The National Vaccine Injury Compensation Program.
The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines. Claims regarding alleged injury or death due to vaccination have a time limit for filing, which may be as short as two years. Visit the VICP website at
How can I learn more?
- Ask your health care provider.
- Call your
local or state health department . - Visit the website of the Food and Drug Administration (FDA) for vaccine package inserts and additional information at
www.fda.gov/vaccines-blood-biologics .
Contact the Centers for Disease Control and Prevention (CDC):
- Call 1-800-232-4636 (1-800-CDC-INFO) or
- Visit CDC's influenza website at
www.cdc.gov/flu
References
Centers for Disease Control and Prevention website. Vaccine Information Statements (VISs): Influenza (flu) vaccine (inactivated or recombinant): What you need to know.
Version Info
Last reviewed on: 7/8/2023
Reviewed by: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update: 02/10/2025.
