A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata
This is a parallel, Phase 2 multinational, multicenter, randomized, double-blind,
placebo-controlled, 3-arm study to investigate the efficacy and safety of subcutaneous
(SC) injections of amlitelimab treatment as monotherapy in participants aged 18 years and
older wi...
Age: 18 years - 66+
Gender: All
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata
Alopecia areata (AA) is a disease that happens when the immune system attacks hair
follicles and causes hair loss. AA usually affects the head and face, but hair loss can
happen on any part of the body. The purpose of this study is to assess how safe,
effective, and ...
Age: 12 - 63 years
Gender: All
Dupilumab in the Treatment of Pediatric Alopecia Areata
This is a prospective, randomized, double-blind, placebo-controlled clinical trial. The study will take place at four sites. This trial will enroll a total of 76 children and adolescents with moderate to severe AA (affecting at least 30% of the scalp) at the time of scr...
Age: 6 - 17 years
Gender: All
Regeneron AA Multicenter (Dupilumab)
This is a prospective, randomized, double blind, placebo-controlled clinical trial. The
study will take place at 4 sites. This trial will enroll a total of 68 patients with
moderate to severe AA (affecting more than 50% of the scalp) at the time of screening
with a t...
Age: 18 years - 66+
Gender: All
PF-06651600 for the Treatment of Alopecia Areata
This is a global Phase 2b/3 study to evaluate the safety and effectiveness of an
investigational study drug (called PF-06651600) in adults and adolescents (12 years and
older) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that
some...
Age: 12 years - 66+
Gender: All
An open-label pilot study to investigate the efficacy of apremilast in the treatment of central centrifugal cicatricial alopecia (CCCA)
"The purpose of this study is to see if the use of apremilast has an effect on the symptoms and progression of central centrifugal cicatricial alopecia (CCCA). Apremilast is an oral PDE4 inhibitor that has anti-inflammatory properties. It inhibits several substances inv...
Age: 18 years - 66+
Gender: Female