RGX-314 is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by loss of vision due to new, leaky blood vessel formation in the retina. Wet AMD is a significant ...

The primary objective of the study is to assess the efficacy of aflibercept compared to laser in patients diagnosed with retinopathy of prematurity (ROP). The secondary objectives of the study are to assess the need for a second treatment modality, to assess the recurre...

This LIGHTSITE III study is a double-masked, sham-controlled, parallel design, prospective multi-site study for the use of PBM as a treatment for visual impairment in subjects with dry AMD. This study is a double-masked, sham-controlled, parallel design prospective, mul...

This study proposes to use a new instrument (AO-OCT/AF: adaptive optics - optical coherence tomography/autofluorescence) combined with a data processing method to image the retinal pigment epithelium (RPE) of the eye in normal subjects and in subjects with age-relate...

The purpose of this study is to learn more about age-related macular degeneration (AMD) by using a new investigational technology, AO-(adaptive optics) OCT (optical coherence tomography) with hyperspectral autofluorescence (AF). While currently there is no cure for AMD,...

Glaucoma is an eye disease that results in damage to cells in the back of the eye known as the retina and poses a major risk to global public health. Primary open angle glaucoma (POAG) is the most common type of glaucoma in the United States. Exfoliation syndrome (XFS) ...

This study is utilizing electrophysiology, called Visual Evoked Potental (VEP) and pattern Electroretinography (ERG) to measure the electrical activity of the visual pathway. VEP measures the electrical activity of the entire vision system. When light enters the eye, it...