Gene-Hunt Gain for Mental Health
Researchers seeking to unpick the complex genetic basis of mental disorders such as schizophrenia have taken a huge step towards their goal. A paper published in Nature this week ties 108 genetic locations to schizophrenia — most for the first time. The encouraging results come on the same day as a US$650-million donation to expand research into psychiatric conditions. “It’s a stunning confirmation that there are many, many genetic factors” said Pamela Sklar, MD, PhD, Professor, Psychiatry, Neuroscience, Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai. “And because these variants are so rare, a larger sample size will be necessary to determine the truly important ones,” said Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai.
-Dr. Joseph D. Buxbaum, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai
-Dr. Pamela Sklar, Professor, Psychiatry, Neuroscience, Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai

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