The Little Girl Who May Hold the Secret to Aging
Brooke Greenberg, who lived near Baltimore with her family, resembled an infant when she was a preteen. The Greenbergs formed a new alliance with Eric Schadt, PhD, Director of the Icahn Institute for Genomics and Multiscale Biology at The Mount Sinai Hospital. When Greenberg’s father first told Dr. Schadt that his daughter, then 19, resembled a toddler, “I was a little skeptical,” said Dr. Schadt. “It seemed hard to believe.” His team has created a line of stem cells from Brooke’s skin, and are using them to grow liver cells, fat cells, neurons, and other building blocks of her body, to study the impact of each mutation, and how it may relate to aging and disease.
-Dr. Eric Schadt, Director of the Icahn Institute for Genomics and Multiscale Biology, Professor and Systems Chair of Genetics and Genomic Studies
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