"Chemo Not Needed For Most Early Breast Cancer - TAILORx" - Roxanne Nelson, BSN, RN
Adjuvant chemotherapy is not necessary for a large proportion of women with early-stage breast cancer, according to new findings that experts agree are "practice changing." The results come from a federally funded study, the Trial Assigning IndividuaLized Options for TReatment (TAILORx), which involved more than 10,000 patients and tested the 21-tumor gene expression assay. Charles L. Shapiro, MD, director of cancer survivorship and translational breast cancer research at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai, emphasized that “this is definitely practice changing.” He added, “We knew about the low-risk patients and could pretty much select those out as they didn't need chemotherapy, and we knew that the high-risk patients did need chemotherapy." However, the situation was quite different with intermediate-risk patients, and there was always a question as to whether they needed chemotherapy. "Many of us were uncertain about what to do," said Dr. Shapiro.
- Charles Shapiro, MD, Director, Cancer Survivorship, Translational Breast Cancer Research, The Tisch Cancer Institute, Professor, Medicine, Icahn School of Medicine at Mount Sinai
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