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"New PRESERVE Analysis Backs Normal Saline Hydration In PCI" - Patrice Wendling

  • Medscape
  • New York, NY
  • (May 03, 2018)

Neither intravenous (IV) sodium bicarbonate nor oral N-acetylcysteine (NAC) were superior to IV saline in reducing 90-day adverse events or contrast-associated acute kidney injury (AKI) in patients who underwent percutaneous coronary intervention (PCI), results of a PRESERVE substudy show. Fellow session co-moderator, George Dangas, MD, PhD, professor of medicine, cardiology, and surgery at the Icahn School of Medicine at Mount Sinai and director of cardiovascular innovation at the Zena and Michael A. Weiner Cardiovascular Institute at The Mount Sinai Hospital said, “This study supports the existing totality of evidence that routine administration of anything else is not superior to simple normal saline hydration” but that “individualized practices may still apply in high-risk individuals or procedures.”

- George D. Dangas, MD, PhD, Professor, Medicine, Cardiology, Surgery, Icahn School of Medicine at Mount Sinai, Director, Cardiovascular Innovation, The Zena and Michael A. Weiner Cardiovascular Institute, The Mount Sinai Hospital

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