"Osteoporosis Drug May Find Use In Cancer Therapy" - Sunderarajan Padmanabhan
A team of researchers at the Icahn School of Medicine at Mount Sinai, led by Mone Zaidi, MD, PhD, professor of medicine, endocrinology, diabetes and bone disease at the Icahn School of Medicine at Mount Sinai, has found that a group of drugs called bisphosphonates, which are used for treatment of osteoporosis, could also be used for treating some lung, breast, and colon cancers. The team led by Dr. Zaidi has filled the gap behind finding out that bisphosphates block abnormal growth signals that pass through a family of proteins called human epidermal growth factor receptors. Bisphosphonates are already approved for human use as effective at preventing bone loss, and have had a long track record of safety. They can be applied to cancers quickly if clinical trials for cancer also prove successful. At the India International Science Festival, which is underway, Dr. Zaidi said the team has already tested with mice models and human cells.
- Mone Zaidi, MD, PhD, Professor, Medicine, Endocrinology, Diabetes and Bone Disease, Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
