"Parkinson Disease and the Gut: Treatment Potential Abounds"- Nicola Davies, PhD
Primarily recognized for its motor symptoms, Parkinson disease (PD) can also be associated with a range of non-motor features, including gastrointestinal (GI) dysfunction and constipation, both of which are key symptoms of inflammatory bowel disease (IBD). A recent study showed a statistically significant increase in the risk for developing PD in patients with IBD. Current evidence highlights the potential role of cross-talk between the enteric and central nervous systems and the pathogenesis of PD. Clearly, more research is needed to better understand the interaction between the gut microbiome and the pathogenesis of PD. Inga Peter, PhD, professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai said, “There are several recent papers that have shown the link between Parkinson disease and the gut microbiome. However, it is still largely unknown if dysbiosis is a risk or consequence of the disease.”
- Inga Peter, PhD, Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai