"Pseudopolyps Not Associated With Greater Colorectal Cancer Risk"
Post-inflammatory polyps (PIPs) are not associated with colorectal neoplasia (CRN) in patients with inflammatory bowel disease (IBD), according to new findings. However, inflammation of the colon was more severe in patients with PIP, who were also more likely to undergo colectomy. “Intervals for surveillance should not be shortened solely based on the presence of PIPs,” said Steven Itzkowitz, MD, professor of medicine, gastroenterology and oncological sciences at the Icahn School of Medicine at Mount Sinai, and colleagues conclude in Gastroenterology. "Our findings should provide some degree of reassurance for clinicians and patients that PIPs are not, in themselves, the worrisome lesions they once were considered. Our data suggest that PIPs are not independently associated with increased risk of any degree of CRN on intermediate-term follow-up, an observation that should be considered in developing future IBD colonoscopic surveillance guidelines," the authors conclude.
— Steven H. Itzkowitz, MD, Professor, Medicine, Gastroenterology, Oncological Sciences, Director, GI Fellowship Program, Icahn School of Medicine at Mount Sinai