Sickle cell disease is caused by an abnormal type of hemoglobin, a protein inside red blood cells that carries oxygen. The abnormal hemoglobin, called hemoglobin S, causes red blood cells to become fragile and look like crescents or sickles. The abnormal red blood cells deliver less oxygen to tissues in the body and can get stuck in small blood vessels, interrupting healthy blood flow. Sickle cell disease is inherited from both parents. It is more common in people of African and Mediterranean descent.

Our Program

The Mount Sinai Sickle Cell Disease Center offers comprehensive care and the most advanced breakthroughs in treatments that dramatically improve outcomes for patients. We join clinical care and scientific research with psychosocial services to provide the best care available anywhere. Our team includes dedicated physicians, advanced practice providers, and social workers who specialize in sickle cell disease and who expertly manage both the acute and chronic complications that sickle cell disease may cause as well as its psychosocial challenges.

Learn about our team members

Research and Clinical Trials

We offer patients with sickle cell disease the opportunity to participate in research studies aimed at improving patient outcomes and quality of life.

Learn more about our research studies, also known as clinical trials

Care for Pediatric Patients

We provide specialized care for children with sickle cell disease and are equipped to treat complications such as stroke and acute chest syndrome in collaboration with Mount Sinai’s Pediatric Intensive Care Unit. We work closely with your child’s pediatrician to diagnose and treat sickle cell disease and to provide patient and family education. We also provide opportunities to participate in support groups, camps, and other extracurricular activities.