Lung metastases
Metastases to the lung; Metastatic cancer to the lung; Lung cancer - metastases; Lung mets
Lung metastases are cancerous tumors that start somewhere else in the body and spread to the lungs.
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Bronchoscopy is a surgical technique for viewing the interior of the airways. Using sophisticated flexible fiber optic instruments, surgeons are able to explore the trachea, main stem bronchi, and some of the small bronchi. In children, this procedure may be used to remove foreign objects that have been inhaled. In adults, the procedure is most often used to take samples of (biopsy) suspicious lesions and for culturing specific areas in the lung.
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A lateral view of a chest x-ray in a patient with central cancer of the lung.
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A chest x-ray in a patient with central cancer of the right lung. Notice the white mass in the middle portion of the right lung (seen on the left side of the picture).
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This x-ray shows a single lesion (pulmonary nodule) in the upper right lung (seen as a light area on the left side of the picture). The nodule has distinct borders (well-defined) and is uniform in density. Tuberculosis (TB) and other diseases can cause this type of lesion.
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This CT scan shows a single lesion (pulmonary nodule) in the right lung. This nodule is seen as the light circle in the upper portion of the dark area on the left side of the picture. A normal lung would look completely black in a CT scan.
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This CT scan shows a cross section of the lungs of a person with lung cancer. The two dark areas in the middle of the screen are the lungs. The light areas in the right lung (on the left of the screen) represent the cancer.
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Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.
Causes
Metastatic tumors in the lungs are cancers that developed at other places in the body (or other parts of the lungs). They then spread through the bloodstream or lymphatic system to the lungs. It is different than lung cancer that starts in the lungs.
Nearly any cancer can spread to the lungs. Common cancers include:
- Bladder cancer
- Breast cancer
- Lung cancer
- Colorectal cancer
- Kidney cancer
- Melanoma
- Ovarian cancer
- Sarcoma
- Thyroid cancer
- Pancreatic cancer
- Testicular cancer
Symptoms
Symptoms may include any of the following:
- Bloody sputum
- Chest pain
- Cough
- Shortness of breath
- Weakness
- Weight loss
Exams and Tests
Your health care provider will examine you and ask about your medical history and symptoms. Tests that may be done include:
- Bronchoscopy to view the airways and take tissue samples, if possible
- Chest CT scan
- Chest x-ray
- Cytologic studies of pleural fluid or sputum
- Lung needle biopsy
- PET scan
- Surgery to take a sample of tissue from the lungs (surgical lung biopsy)
Treatment
Chemotherapy is often used to treat metastatic cancer to the lung. Surgery to remove the tumors may be done when any of the following occurs:
- The cancer has spread to only limited areas of the lung
- The lung tumors can be completely removed with surgery
However, the main tumor must be curable, and the person must be strong enough to go through the surgery and recovery.
Other treatments include:
- Radiation therapy
- Immunotherapy
- Targeted systemic therapy
- The placement of stents inside the airways
- Laser therapy
- Using local heat probes to destroy the cancer
- Using very cold temperature to destroy the cancer
Support Groups
You can ease the stress of illness by joining a support group where members share common experiences and problems.
Outlook (Prognosis)
A cure is unlikely in most cases of cancers that have spread to the lungs. But the outlook depends on the main cancer. In some cases, a person can live more than 5 years with metastatic cancer to the lungs.
Possible Complications
Complications of metastatic tumors in the lungs may include:
- Fluid between the lung and chest wall (pleural effusion), which can cause shortness of breath or pain when taking a deep breath
- Further spread of the cancer
When to Contact a Medical Professional
Contact your provider if you have a history of cancer and you develop:
- Coughing up blood
- Persistent cough
- Shortness of breath
- Unexplained weight loss
Prevention
Not all cancers can be prevented. However, many can be prevented by:
- Eating healthy foods
- Exercising regularly
- Limiting alcohol consumption
- Not smoking
References
Arenberg DA, Reddy RM. Metastatic malignant tumors. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 79.
Hayman J, Naidoo J, Ettinger DS. Lung metastases. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 57.
Wald O, Izhar U, Sugarbaker DJ. Lung, chest wall, pleura, and mediastinum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 58.
Version Info
Last reviewed on: 6/17/2024
Reviewed by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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