Symptoms of multiple myeloma vary from one patient to another and are often similar to symptoms of other conditions. You may experience one or more symptoms – or, during early stages of the disease, you may not experience any symptoms. Results of routine blood work might be the first indication of multiple myeloma.

Symptoms of multiple myeloma may include:

• Bone pain, especially in the back or ribs
• Bones that fracture or break easily
• Easy bruising or bleeding
• Fatigue
• Fever for no obvious reason or frequent infections
• Numbness and weakness of the arms or legs
• Shortness of breath

Increased levels of calcium in the blood (hypercalcemia), resulting from multiple myeloma, can cause:

• Confusion
• Constipation
• Excessive thirst
• Fatigue
• Frequent urination
• Loss of appetite
• Nausea or vomiting
• Restlessness